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Allele : Pax2<tm1.2Akio> paired box 2; targeted mutation 1.2, Akio Kobayashi

Primary Identifier  MGI:6154955 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pax2
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was flanked by loxP sites and an FRT-flanked PGK-neomycin selection cassette was introduced following the second loxP site. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 2 causing a frame-shift mutation with a premature translational termination producing a transcript encoding only the first 14 amino acids.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Pax2<del>,
  • Pax2<del>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories