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Allele : Smchd1<tm1.1Maar> SMC hinge domain containing 1; targeted mutation 1.1, Silvere van der Maarel

Primary Identifier	MGI:6155687	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Smchd1
Transmission	Germline	Strain of Origin	B6.Cg-Thy1<a>
Is Recombinase	false	Is Wild Type	false

molecularNote

A targeting construct introduced loxP sites surrounding exon 4 of mouse Smchd1 gene and a neomycin cassette flanked by Frt sites by recombineering. The neomycin cassette was removed by crossing with the FLPe knockin mouse strain.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Smchd1<fl>,
Smchd1<fl>

earliestPublication:
de Greef JC, et al. (2018) Smchd1 haploinsufficiency exacerbates the phenotype of a transgenic FSHD1 mouse model. Hum Mol Genet 27(4):716-731

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

7 Publication categories

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