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Allele : Aass<em1(IMPC)Tcp> aminoadipate-semialdehyde synthase; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6156438 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Aass
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with four single guide RNAs having spacer sequences of GATGAGGACCTAGGTGGGTG and GCTTCCTTAGGATACTAAGC targeting the 5' side and GTAACTCCACCTATCCTTTC and GAATGAGTGACCATTCAATA targeting the 3' side of exon ENSMUSE00000325812 and ENSMUSE00001242969 resulting in a 473-bp deletion Chr6:23114817-23115289_insGCATCAAGTGTTT (GRCm39).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

6 Publication categories