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Allele : Auts2<tm1Mhos> autism susceptibility candidate 2; targeted mutation 1, Mikio Hoshino

Primary Identifier  MGI:6156948 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Auts2
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 8 and a loxP site and a FRT-flanked neomycin cassette were inserted downstream of exon 8 in opposite orientation. Immunohistochemistry indicates that both the full-length and shorter splicing variant (variant 1 with transcriptional start site in exon 7) proteins are almost completely eliminated in the brain of homozygotes.
  • mutations:
  • Insertion
  • synonyms:
  • Auts2<neo>,
  • Auts2<neo>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories