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Allele : Spred3<em1(IMPC)Tcp> sprouty-related EVH1 domain containing 3; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6156549 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Spred3
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0439 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of GTGGGTGTACTGGTGGCTTG and GTTAGGGAGAACGCTCAAAC targeting the 5' side and TATTGAGCTTGAGGTTGGCC and TACTGGTGTGTCACCAGGTG targeting the 3' side of a critical region. This resulted in a 1928 bp deletion & 12bp insTAAAAGGGATAA of Chr7 from 29166134 to 29168061. (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

5 Publication categories