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Allele : Glrb<em1(IMPC)Tcp> glycine receptor, beta subunit; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6156599 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Glrb
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0720 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of TCTACTAGGAAAAGTCTTGG and CTCGGGTGACTGCTGACTAA targeting the 5' side and ATATAGGTATGAAGACTGGA and TTAGGCTCTGAACATTGATG targeting the 3' side resulting in a 143-bp deletion of Chr3 from 80879590 to 80879732 and a 1-bp deletion Chr3:80879862 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele