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Allele : Glra1<tm1.1Wxi> glycine receptor, alpha 1 subunit; targeted mutation 1.1, Wei Xiong
Primary Identifier  MGI:6157053 Allele Type  Targeted
Attribute String  Hypomorph Gene  Glra1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  The serine at position 296 in exon 8 was converted to an alanine and an FRT flanked neo cassette was inserted in intron 8 via homologous recombination. Flp mediated recombination removed the neo cassette. The mutation appears to suppress the interaction between dehydroxylcannabidiol and the receptor.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • GlyRalpha1<S296A>,
  • GlyRalpha1<S296A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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