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Allele : Syt2<tm2.1Sud> synaptotagmin II; targeted mutation 2.1, Thomas C Sudhof

Primary Identifier  MGI:6157360 Allele Type  Targeted
Attribute String  Conditional ready Gene  Syt2
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6J)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct includes a loxP site inserted into intron 1 and the following inserted into intron 2: loxP2 - inverted FRT1 - loxP1 - FRT2 - inverted neomycin casstte - inverted FRT1 - inverted Syt9 coding sequence - inverted loxP1 - inverted loxP2 - FRT2. The Syt9 cDNA incorporated in the allele (intended to function as a conditional knock-in) is non-functional. Flp-mediated recombination excised the region between the two FRT2 sites, leaving a loxP1 site in intron 1 and the following in intron 2: loxP5171-inverted FRT1-loxP1-FRT2.
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories