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Allele : Mllt6<em1(IMPC)Tcp> myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6156510 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Mllt6
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele from project TCPR0432 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of TCCTGTGACATTGCGTTTAC and CTGGACAGTACTGATCTGGA targeting the 5' side and GCCACGCCATGCTTAGGTCT and GGTAGGATGCTCCCACTCGG targeting the 3' side of exon ENSMUSE00001228124 (exon 5) resulting in a 316 bp deletion of Chr11 from 97666685 to 97667000, with a 19 bp insertion of GACGCCACGCCATGCTTAG.(GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

5 Publication categories