| Primary Identifier | MGI:6160877 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Acan |
| Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | EUCOMM |
| molecularNote | Flp-mediated recombination of the parental Acantm1a(EUCOMM)Hmgu allele excised the splice acceptor-lacZ reporter sequence and the neomycin selection cassette from the third intron, leaving the critical exon 4 flanked by loxP sites. Exposure to Cre recombinase will delete exon 4, resulting in a null mutation. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. |
