Primary Identifier | MGI:6162028 | Allele Type | Chemically induced (ENU) |
Attribute String | Null/knockout | Gene | Mitf |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This mutation was induced by treatment with ethylnitrosourea as part of a genetic screen performed at the Novartis Institute for Functional Genomics. Sequence analysis shows that the mutation is a C-to-T change at nucleotide position 205 of the cDNA, which introduces a stop codon in exon 2A, changing glutamine at position 26 of the MITF protein to STOP. |