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Allele : Stt3b<em1(IMPC)J> STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae); endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6188000 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Stt3b
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 4 guide sequences CATTTCCTGCTAAGGGACGA, ACAGTAGTAGCCTCTTCACA, TTGAGTTTAAAAGCTTTTGG and TTTTAACAGACAAAAGTGAA, which resulted in a 633 bp deletion beginning at Chromosome 9 position 115,280,019 bp and ending after 115,280,651 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000219753 (exon 2) and 524 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 103 and early truncation 3 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories