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Allele : Etfbkmt<em1Yshk> electron transfer flavoprotein beta subunit lysine methyltransferase; endonuclease-mediated mutation 1, Yoichi Shinkai

Primary Identifier  MGI:6188078 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Etfbkmt
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 mutagenesis generated a 17 bp deletion in exon 4 which encodes the methyltransferase domain. Western blot analysis showed that protein expression levels were undetectable in all tissues tested in homozygous mutant mice. No tri-methylation of electron transfer flavoprotein beta subunit (ETFB) was detected in liver samples from homozygous mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Mettl20 KO,
  • Mettl20 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele