Primary Identifier | MGI:6200002 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Trpa1 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced T to C transition at base pair 14,884,116 (v38) on chromosome 1, or base pair 34,899 in the GenBank genomic region NC_000067 encoding Trpa1. The mutation corresponds to residue 2,585 in the mRNA sequence NM_177781 within exon 21 of 27 total exons. The mutation results in a leucine (L) to proline (P) substitution at position 853 (L853P) in the TRPA1 protein. |