Primary Identifier | MGI:6200035 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Mc4r |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced T to A transversion at base pair 66,859,180 (v38) on chromosome 18, or base pair 1,308 in the GenBank genomic region NC_000084 for the Mc4r gene. The mutation corresponds to residue 1,308 in the mRNA sequence NM_016977 within exon 1 of 1 total exons. The mutation results in substitution of tyrosine 287 for a premature stop codon (Y287*). |