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Allele : Tg(Myh6-Prkaca)2Eno transgene insertion 2, Eric N Olson
Primary Identifier  MGI:6193913 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-Prkaca)2Eno
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The alpha-MHC promoter drives the expression of the PKA-Calpha cDNA. Overexpression of the catalytic subunit results in constitutive activation of the enzyme without a requirement for cAMP. Assays for activity in heart extracts show that Prkaca activity is elevated 8-fold in line 2.
  • mutations:
  • Insertion
  • synonyms:
  • alphaMHC-PKA Tg2,
  • alphaMHC-PKA Tg2
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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