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Allele : Gt(ROSA)26Sor<tm1(CAG-EGFP)Maito> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Mamoru Ito

Primary Identifier  MGI:6202418 Allele Type  Targeted
Attribute String  Conditional ready, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6JJic
Is Recombinase  false Is Wild Type  false
description  ES cell line = Wit 9 (C57BL/6JJic).
molecularNote  A construct containing the CAG promoter with a VloxP-STOP-VloxP cassette preceding EGFP sequence was inserted into the intron of the Gt(ROSA)26Sor locus via homologous recombination in Wit 9 ES cells. VCre-mediated recombination of this allele results in the expression of the EGFP reporter driven by the CAG promoter. VCre/VloxP is a site-specific recombination system, which was derived from plasmid p0908 of Vibrio sp. VCre is a recombinase that recognizes its own specific target sites (VloxP).
  • mutations:
  • Insertion
  • synonyms:
  • VloxP-EGFP KI,
  • VloxP-EGFP KI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories