Primary Identifier | MGI:6199947 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Pax5 |
Inheritance Mode | Dominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced A to G transition at base pair 44,679,526 (v38) on chromosome 4, or base pair 30,915 in the GenBank genomic region NC_000070. The mutation corresponds to residue 804 in the mRNA sequence NM_008782 within exon 5 of 10 total exons. The mutation results in an aspartic acid to glycine substitution at position 173 (D173G) in the canonical variant of the PAX5 protein. |