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Allele : Ctla4<m1Btlr> cytotoxic T-lymphocyte-associated protein 4; mutation 1, Bruce Beutler

Primary Identifier  MGI:6200388 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Ctla4
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced T to C transition at base pair 60,912,491 (v38) on chromosome 1, or base pair 3,467 in the GenBank genomic region NC_000067. The mutation corresponds to residue 324 in the mRNA sequence NM_009843 within exon 2 of 4 total exons. The mutation results in a tyrosine to histidine substitution at position 60 (Y60H) in the CTLA4 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • complementary,
  • complementary
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories