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Allele : Lrfn1<em1(IMPC)J> leucine rich repeat and fibronectin type III domain containing 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6200431 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Lrfn1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGCCCGGAGGAGAAGGGGCC and CAGATGACTCCCTAGTCTAC, which resulted in a 1398 bp deletion beginning at Chromosome 7 position 28,458,664 bp and ending after 28,460,061 bp (GRCm38/mm10). This mutation deletes 1398 bp of ENSMUSE00000365917 (exon 1) and is predicted to cause a change of amino acid sequence and early truncation after residue 4.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories