Primary Identifier | MGI:6200327 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Ikzf1 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced C to T transition at base pair 11,768,961(v38) on chromosome 11, or base pair 83,993 in the GenBank genomic region NC_000077 encoding Ikzf1. The mutation corresponds to residue 1,486 in the mRNA sequence NM_001025597 within exon 8 of 8 total exons. The mutation results in substitution of glutamine 310 for a premature stop codon (Q310*) in variant 1 of the IKZF1 protein. |