| Primary Identifier | MGI:6202984 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Sorl1 |
| Strain of Origin | B6(SJL)-Apoe<tm1.1(APOE*4)Adiuj> Trem2<em1Adiuj>/J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Plasmids encoding a single guide RNA designed to introduce the A528T point mutation (GCC to ACC; modeling human variant rs2298813) and silent R529R mutation into the gene and the cas9 nuclease were introduced into the cytoplasm of fertilized eggs with well recognized pronuclei. |
