| Primary Identifier | MGI:6194379 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Nr1h3 |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting construct inserted into intron 4 a loxP site, alox2272 site, a reverse orientation modified exon 5 in which a nucleotide substitution (T to G) results in the amino acid substitution of alanine for serine at position 196 (S196A; ENSMUSG00000002108), and a loxP site. An additional lox2272 site was inserted downstream of the endogenous exon 5. Flp-mediated recombination removed the selection cassette inserted downstream of the modified exon 5. |
