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Allele : Ifitm5<em1Pmof> interferon induced transmembrane protein 5; endonuclease-mediated mutation 1, Pierre Moffatt

Primary Identifier  MGI:6195290 Allele Type  Endonuclease-mediated
Gene  Ifitm5 Strain of Origin  CD-1
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a single -14C to T base change in the 5'-UTR, creating a novel ATG start site adding 5 residues (MALEP) in frame with the natural coding sequence. This is a mutation seen in some osteogenesis imperfecta type V patients.
  • mutations:
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories