Primary Identifier | MGI:6195290 | Allele Type | Endonuclease-mediated |
Gene | Ifitm5 | Strain of Origin | CD-1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a single -14C to T base change in the 5'-UTR, creating a novel ATG start site adding 5 residues (MALEP) in frame with the natural coding sequence. This is a mutation seen in some osteogenesis imperfecta type V patients. |