Primary Identifier | MGI:6195189 | Allele Type | Endonuclease-mediated |
Attribute String | Recombinase | Gene | Lyz2 |
Transmission | Germline | Strain of Origin | BALB/cJ |
Is Recombinase | true | Is Wild Type | false |
description | ES Cell Line = PRX-BALB/cJ 9 |
molecularNote | CRISPR/cas9 endonuclease mediated genome editing is used to introduce a nucleus-localized (NLS) Cre recombinase followed by a FRT-flanked neomycin cassette into the ATG start codon of the gene. Flp-mediated recombination removed the FRT-flanked neo cassette. |