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Allele : Ptk2<tm1.1Meve> PTK2 protein tyrosine kinase 2; targeted mutation 1.1, Alexander Meves

Primary Identifier	MGI:6195562	Allele Type	Targeted
Gene	Ptk2	Transmission	Germline
Strain of Origin	Not Specified	Is Recombinase	false
Is Wild Type	false

molecularNote

A tyrosine (TAT) to phenylalanine (TTT) mutation was inserted in exon 15 at codon 397 and an FRT flanked neo cassette was inserted downstream of exon 15 via homologous recombination. Flp mediated recombination removed the neo cassette.

mutations:
Single point mutation

cellLines:
Not Specified

synonyms:
FAK Y397F,
FAK Y397F

earliestPublication:
Heim JB, et al. (2017) Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix. Proc Natl Acad Sci U S A 114(15):3933-3938

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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