Primary Identifier | MGI:6195711 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Abcc6 |
Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
Is Recombinase | false | Is Wild Type | false |
Project Collection | EUCOMM |
molecularNote | The L1L2_Bact_P cassette was inserted at position 46019130 of Chromosome 7 upstream of exon 5. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 6 at position 46017355. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 5 and 6 floxed. |