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Allele : Rr57<em2Ddu> regulatory region 57; endonuclease-mediated mutation 2, Denis Duboule
Primary Identifier  MGI:6195734 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr57
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  An inversion was generated between the regions targeted by sgRNAs 5'-GAGATTCTACTCCTAAGCCC-3' and 5'-ATTCCCCGGGAAATAGCCCA-3', using CRISPR/Cas9 technology. This CpG island contains a bidirectional promoter for Hoxd1 and Haglr and also encompasses the first exons of both genes.
  • mutations:
  • Inversion
  • synonyms:
  • HoxD<Inv(CpG114)>,
  • HoxD<Inv(CpG114)>
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1 Feature

Genome

0 Expresses

2 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories





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