| Primary Identifier | MGI:6201357 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Iws1 |
| Transmission | Germline | Strain of Origin | 129S1/SvImJ or C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The L1L2_Bact_P cassette was inserted at position 32215869 of Chromosome 18 upstream of the exon 4 (Build GRCm39). The cassette is composed of an FRT site followed by a lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, an SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the exon 4 at position 32216763. Exon 4 is thus flanked by loxP sites. Cre-mediated recombination without flp expression created a reporter knockout mouse. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml |
