| Help | About | Contact Us

Allele : Gpr119<tm1.1Ddr> G-protein coupled receptor 119; targeted mutation 1.1, Daniel J Drucker

Primary Identifier	MGI:6199061	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Gpr119
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

LoxP sites were inserted upstream of exon 1 and into intron 2. An FRT site flanked neomycin resistance gene cassette that was also inserted was removed through subsequent flp-mediated recombination. This leaves a conditional-ready allele with exon 1 floxed.

mutations:
Insertion

cellLines:
Not Specified

earliestPublication:
Panaro BL, et al. (2017) beta-Cell Inactivation of Gpr119 Unmasks Incretin Dependence of GPR119-Mediated Glucoregulation. Diabetes 66(6):1626-1635

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76637587

MouseMine