| Primary Identifier | MGI:6195826 | Allele Type | Other |
| Gene | Igkj5 | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A mature B cell, where the the immunoglobulin kappa chain complex had undergone Igk-V to Igkj5 recombination, was isolated and reprogrammed to an iPSC (induced pluripotent stem cell). This iPSC was then used to create a homozygous mouse line where all cells contain this allele. The mouse from which the B cells were isolated is a reprogrammable mouse containing the Col1a1tm1(tetO-Pou5f1,-Klf4,-Sox2,-Myc)Hoch and Gt(ROSA)26Sortm1(rtTA*M2)Jae alleles which allow for the reprogramming to be induced by doxycycline. |
