| Primary Identifier | MGI:6196043 | Allele Type | Transgenic |
| Attribute String | Conditional ready, Inserted expressed sequence, Reporter | Gene | Tg(CAG-Alk*F1174L,-luc)60Jhsc |
| Strain of Origin | C57BL/6 or FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | This transgene consists of the 1.8-kb chicken beta-actin promoter (pCAG), loxP-flanked GFP cassette acting as a STOP cassette, ALK cDNA containing the phenylalanine to leucine mutation at amino acid 1174 (F1174L), IRES, and a fusion construct encoding firefly luciferase and chicken ovalbumin. This line showed the highest luciferase activity upon cre-mediated removal of the GFP. |
