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Allele : Cyp4f39<em1(IMPC)J> cytochrome P450, family 4, subfamily f, polypeptide 39; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6201606 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Cyp4f39
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTAGAGTGGGGAGCAACTCA and GATAGAAGTTCACCAAACTG, which resulted in a 437 bp deletion beginning at Chromosome 17 position 32,470,647 bp and ending after 32,471,083 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000511656 (exon 2) and 292 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 74 and early truncation 13 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele