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Allele : Actb<em1Erv> actin, beta; endonuclease-mediated mutation 1, James Ervasti

Primary Identifier  MGI:6209780 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Actb
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  TALEN-based genome editing was used to introduce 8 nucleotide alterations, which function to exchange the translation of beta-actin D2-4, V10 to gamma-actin E2-4, I10, and to disrupt TALEN re-binding to the edited locus. Mice are null for the beta-actin protein.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Actb<c-g>,
  • Actb<c-g>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories