| Primary Identifier | MGI:6278934 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Atp2b1 |
| Strain of Origin | (FVB/N x (C57BL/6J x DBA/2J))F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The human CHMP2B cDNA containing a missense mutation in the splice acceptor site of exon 6 that is a mutation identified in human familial FTD, and tagged with two hemagglutinin sequences, is under the control of the mouse Thy1.2 promoter. The transgene integrated within chromosome 10: 98950250-98968278 in the Atp1b1 gene within the large first intron. Atp2b1 mRNA levels are not modified although a trend of a decrease is seen in homozygous mice. One line was established. |
