| Primary Identifier | MGI:6209386 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Dennd6a |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGTATGCCGAAAATTCTAGT and TACATGACGAGTAGCCAGCA, which resulted in a 352 bp deletion beginning at Chromosome 14 position 26,592,173 bp and ending after 26,592,524 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000355312, and ENSMUSE00000398626 (exons 2 and 3) and 270 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 77 and early truncation 35 amino acids later. |
