Primary Identifier | MGI:6257033 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase | Gene | Tg(Pthlh-cre/ERT2)909Nono |
Strain of Origin | (C57BL/6 x SJL)F1 | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-27F7) containing the entire mouse parathyroid hormone-like peptide (Pthlh) gene. This BAC was modified to replace the native start codon of the Pthlh gene with a cre/ERT2 fusion gene (Cre recombinase fused to a human estrogen receptor ligand-binding domain), followed by an SV40 polyadenylation sequence. |