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Allele : Hibch<em1(IMPC)Tcp> 3-hydroxyisobutyryl-Coenzyme A hydrolase; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:6257527 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Hibch
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele from project TCPR1207 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of CCTTCATAAAACACTCGCAG and CCAAACATAAGAGACGATAA targeting the 5' side and ATGTTGGTGATACTAGGGGC and GAGTCTGCACACAGCGGGTT targeting the 3' side of a critical exon. This resulted in a 496-bp deletion Chr1:52862152 to 52862647 (GRCm38).
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

4 Publication categories