| Primary Identifier | MGI:6241421 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Fam53c |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ACTGCATTTTTGAGGAGGAG and GTTAAAATTCAATACTGCCA, which resulted in a 1151 bp deletion beginning at Chromosome 18 position 34,767,928 bp and ending after 34,769,078 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000483922 (exon 4) and 366 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 46 and early truncation 27 amino acids later. |
