|  Help  |  About  |  Contact Us

Allele : Dag1<tm4Kcam> dystroglycan 1; targeted mutation 4, Kevin P Campbell

Primary Identifier  MGI:6257835 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Dag1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
description  The version of this allele that does not contain the neomycin selection cassette, Dag1tm4.1Kcam, has been analyzed.
molecularNote  A nucleotide substitutions in exon 3 resulted in the amino acid substitution of methionine for threonine at position 190 (T190M). This mutation corresponds to the T192M mutation identified in humans with Limb-Girdle Muscular Dystrophy. A floxed neo cassette was inserted upstream of exon 3.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Dag1<T190M>,
  • Dag1<T190M>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories