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Allele : Gpx4<tm1.1Adbo> glutathione peroxidase 4; targeted mutation 1.1, Astrid Borchert
Primary Identifier  MGI:6257859 Allele Type  Targeted
Gene  Gpx4 Transmission  Germline
Strain of Origin  (C57BL/6NTac x 129S6/SvEvTac)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 2 was replaced with a modified one in which the selenocysteine (TGA) was mutated to an alanine encoding triplet (GCA) at position 46 (Sec46Ala). Flp-mediated recombination removed the FRT- and loxP-flanked neomycin resistance cassette inserted downstream of exon 4.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Sec46Ala-Gpx4<->,
  • Sec46Ala-Gpx4<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





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