Primary Identifier | MGI:6268758 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Yap1 |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced G to A transition at base pair 8,004,284 (v38) on chromosome 9, or base pair 313 in the GenBank genomic region NC_000075 encoding Yap1. The mutation corresponds to residue 313 in the mRNA sequence NM_001171147 within exon 1 of 9 total exons. The mutation results in a glycine to aspartic acid substitution at amino acid 36 (G36D) in the YAP1 protein. |