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Allele : Lepr<m8Btlr> leptin receptor; mutation 8, Bruce Beutler

Primary Identifier  MGI:6269382 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Lepr
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced C to A transition at base pair 101,792,023 (v38) on chromosome 4, or base pair 74,890 in the GenBank genomic region NC_000070. The mutation corresponds to residue 3,172 in the mRNA sequence NM_146146 within exon 18 of 19 total exons. The mutation results in a proline to threonine substitution at position 874 (P874T) in the LEPR protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • fluffy,
  • fluffy
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories