Primary Identifier | MGI:6268726 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Irs2 |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced T to G transversion at base pair 10,987,012 (v38) on chromosome 8, or base pair 21,420 in the GenBank genomic region NC_000074 encoding Irs2. The mutation corresponds to residue 3,964 in the mRNA sequence NM_001081212 within exon 2 of 2 total exons. The mutation results in substitution of the stop codon at position 1,322 to a glycine (*1322G) in the IRS2 protein. |