|  Help  |  About  |  Contact Us

Allele : Irs2<M1Btlr> insulin receptor substrate 2; mutaiton 1, Bruce Beutler

Primary Identifier  MGI:6268726 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Irs2
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced T to G transversion at base pair 10,987,012 (v38) on chromosome 8, or base pair 21,420 in the GenBank genomic region NC_000074 encoding Irs2. The mutation corresponds to residue 3,964 in the mRNA sequence NM_001081212 within exon 2 of 2 total exons. The mutation results in substitution of the stop codon at position 1,322 to a glycine (*1322G) in the IRS2 protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Dum_dum,
  • Dum_dum
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele