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Allele : Insr<m1Btlr> insulin receptor; mutation 1, Bruce Beutler

Primary Identifier  MGI:6268730 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Insr
Inheritance Mode  Recessive Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced T to C transition at base pair 3,161,770 (v38) on chromosome 8, or base pair 117,880 in the GenBank genomic region NC_000074 encoding Insr. The mutation corresponds to residue 3,739 in the mRNA sequence NM_010568 within exon 17 of 21 total exons. The mutation results in a serine (S) to proline (P) substitution at position 1,084 (S1084P) in the InsR protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • gummi_bear,
  • gummi_bear
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories