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Allele : Crbn<tm1.1Ble> cereblon; targeted mutation 1.1, Benjamin L Ebert

Primary Identifier  MGI:6258757 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Crbn
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector contains an FRT- and loxP-flanked neomycin cassette inserted upstream of exon 11 followed by a point mutation substitution isoleucine for the corresponding human residue, valine (I391V) in exon 11. Flp-mediated recombination removed the FRT-flanked neo cassette.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Crbn<I391V>,
  • Crbn<I391V>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele