Primary Identifier | MGI:6259153 | Allele Type | Targeted |
Attribute String | Conditional ready, Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A construct containing a loxP-flanked neo and STOP cassette was inserted between the chicken actin promoter (CAG) and the murine Tpp1 cDNA was integrated into the ROSA26 locus by homologous recombination. This creates a conditional-ready allele from which the gene will only be expressed after cre-mediated recombination of the STOP cassette. |