| Primary Identifier | MGI:6259589 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Secisbp2l |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences, AATTAAGCATTAAAGGCCAA and TTATCAGCAAAAAAAGCTGA, which resulted in a 562 bp deletion beginning at Chromosome 2 position 125,773,086 bp and ending after 125,773,647 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000324940 (exon 3) and 237 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 71 and early truncation 4 amino acids later. |
