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Allele : Brca1<em1Nki> breast cancer 1, early onset; endonuclease-mediated mutation 1, The Netherlands Cancer Institute
Primary Identifier  MGI:6276141 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Brca1
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR-targeting with gRNA(5'-TTTCCTGCTGCAGCTTTATCAGG-3') introduced a point mutation in exon 12 L1363P (CTG>CCC) and silent mutations in K1362K (AAG>AAA) and I1361I (ATA>ATT).
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Brca1 L1363P,
  • Brca1 L1363P
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories





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